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Jennifer Parisella of Middletown was pronounced dead at the scene on southbound I-87 near Exit 1 and the Willis Avenue Bridge, police said.
A 14-year-old girl who was a passenger in the van, a 2003 Ford Econoline, is in critical condition. Two other passengers, a 28-year-old man and 12-year-old boy, were also hospitalized and are in stable condition.
The girl, identified as Sky Mendoza, is Parisella's stepdaughter, according to the New York Post, and the boy, Orlando Mendoza, Jr., her stepson. The 28-year-old is Parisella's brother, according to ABC 7.
Parisella, who worked on a farm with her family, was on en route to the city with produce, according to multiple reports.
The 42-year-old driver of the tractor-trailer was also hospitalized and is in stable condition.
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